"The NeoNET Africa network seeks to address the pressing issue of neonatal deaths due to bacterial infections in sub-Saharan Africa. With a focused multidisciplinary approach, the network aims to consolidate research, foster collaborations, and leverage existing expertise to provide concrete solutions."
A network of professionals and families committed to addressing the evidence gap for how we can best identify, treat and prevent neonatal sepsis in the smallest, most vulnerable babies in sub-Saharan Africa. Where you are born should not stop you receiving effective care.
Our work aims to find the best ways to safely reduce unnecessary antibiotic use in babies, prioritising resources for those babies most in need, and the best ways to prevent the spread of infection between babies, even with scarce resources.
A federated data platform to maximise the data we have while preserving data sovereignty.
Developing best practice guidelines for use in low-resource settings.
Neonatal sepsis is the third leading cause of newborn death worldwide, yet the antibiotics used to treat it have barely changed in 50 years — and resistance is rising. NeoSep1 is a multi-country adaptive platform trial testing new antibiotic combinations to find better, safer treatments.
Our data infrastructure underpins the trial at sites across Africa and Asia, enabling researchers to recruit patients faster and generate evidence that will directly change treatment guidelines globally.
Every photograph here represents a life that matters — and the dedication of healthcare workers across Africa who fight every day to give newborns the best possible start.
Zimkhitha Ndinisa & Avumile reviewing a newborn's chart · Tygerberg Hospital, 2024
Prof. Angela Dramowski · Principal Investigator, NeoSep1 · Tygerberg Hospital, 2022
Research and laboratory teams drive the evidence base for better neonatal treatment
A mother stays close as her newborn recovers in the neonatal ward · Tygerberg, 2024
Okwenathi Sibango, diagnosed with neonatal sepsis, receiving care · Tygerberg, 2022
Laboratory analysis underpins the antibiotic stewardship research driving NeoSep1
Our team spans paediatricians, nurses, data scientists, and global health researchers united by one goal: to stop the spread of antibiotic resistance in babies in sub-Saharan Africa.